White Plains Hospital

Annual Report 2015-2016

White Plains Cancer Program 2014-2015 Annual Report

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| WHITE PL AINS HOSPITAL • CANCER CARE 14 Clinical Trials LUNG (CONTINUED): CA209-370 CHECKMATE: A Master Protocol of Phase 1/2 Studies of Nivolumab in Advanced NSCLC Using Nivolumab as Maintenance after Induction Chemotherapy or as First-line Treatment Alone or in Combination with Standard of Care Therapies (D. Costin) E4512: A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Placebo for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein (J. Raff) EA5142: A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers (ANVIL) (J. Raff) IELCAP: White Plains Hospital Lung Cancer Screening Program (C. Chin) Lung Biopsy: Next Generation DNA Sequencing of Malignant Tumors Obtained by Lung Biopsy: A Prospective Clinical Registry (D. Costin) MELANOMA: E3612: A Randomized Phase II Trial of Ipilimumab With or Without Bevacizumab in Patients with Unresectable Stage III or Stage IV Melanoma (D. Costin) MULTIPLE MYELOMA: E3A06: Randomized Phase III Trial of Lenalidomide Versus Observation Alone in Patients with Asymptomatic High-Risk Smoldering Multiple Myeloma (J. Raff) NEWLY DIAGNOSED / QUALITY OF LIFE: DEALS-EPS: Dietary Education and Livestrong Exercise Program Study (D. Costin) OVARIAN: GOG-0281: A Randomized Phase II/III Study to Assess the Efficacy of Trametinib (GSK 1120212) in Patients with Recurrent or Progressive Low-Grade Serous Ovarian Cancer or Peritoneal Cancer NRG-GY004: A Phase III study comparing single-agent olaparib or the combination of cediranib and olaparib to standard platinum-based chemotherapy in women with recurrent platinum-sensitive ovarian, fallopian tube, or primary peritoneal cancer (D. Costin) NRG-GY005: A Randomized Phase II/III study of the combination of Cediranib and Olaparib compared to Cediranib or Olaparib alone, or Standard of care chemotherapy in women with recurrent platinum- resistant or –refractory ovarian, fallopian tube, or primary peritoneal cancer (COCOS) (D. Costin) PANCREATIC: PCEDP: Early Detection for Pancreatic Adenocarcinoma in Patients at Elevated Risk (J. Raff) PROSTATE: PCORI: Development of Practice Outcome Measures to Account for Individual Differences and Temporal Changes in Quality of Life Appraisal S1216: A Phase III Randomized Trial Comparing Androgen Deprivation Therapy + TAK-700 with Androgen Deprivation Therapy + Bicalutamide in Patients with Newly Diagnosed Metastatic Hormone Sensitive Prostate Cancer (D. Costin) SARCOMA: A091304: A Phase I/Randomized Phase II Study of MLN0128 vs. Pazopanib in Patients with Locally Advanced/Unresectable and/or Metastatic Sarcoma SOLID TUMORS AND LYMPHOMAS: EAY131: Molecular Analysis for Therapy Choice (MATCH) (J. Monroe) SUPPORTIVE CARE: Rocktape: A Randomized Placebo Control Trial for Pain Management in Cancer Patients Using Best Supportive Care for Pain Management With or Without Rocktape (D. Costin) Tommie Copper: Pilot Evaluation of Tommie Copper Material and Its Impact on Pain Control (D. Costin)

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