IT MAY BE possible to determine which
localized prostate cancers will metas-
tasize, even when caught very early on,
according to a recent study published in
Nature Cancer.
" We identif ied a 16-gene signature
that is enriched in bone meta sta sis,
and that can predict whether localized
tumors would metastasize early, as well
as whether metastases are less likely to
respond to current standard-of-care treat-
ments," says lead author Juan Arriaga,
PhD, a postdoctoral research scientist at
Columbia University Vagelos College of
Physicians and Surgeons and the school's
Abate-Shen Lab.
The research, while still in early stages,
could have a significant impact on prostate
cancer treatment.
WHY IT MATTERS
One in eight men will get prostate cancer
in his lifetime, according to the American
Ca ncer Societ y. For t unately, due to
Can a Genetic Signature Predict
Which Prostate Cancers Spread?
BY CARI WADE GERVIN
A NE W STUDY COULD LE AD TO BE T TER TAILORING OF TRE ATMENTS TO INDIVIDUAL PATIENTS.
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