MDNews - South Central Pennsylvania

April 2023

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TODD, 39, AN attorney, had been active and fit his entire life. When he started feeling extreme fatigue and unusual pains, he assumed it was a combination of approaching middle age and parenting a rambunctious toddler during a pandemic. As his symp- toms got worse, he pushed for more answers. Ultimately, Todd was diagnosed with multiple sclerosis. "My doctors have been very optimistic, but it's been hard to see it from my particular perspective," Todd says. However, new research released shortly after Todd's diagnosis may unlock a key clue for future MS treatment and even prevention. In a longitudinal analysis published in Science in January 2022, researchers found that the Epstein-Barr virus (EBV) is likely one cause of MS, especially in people whose EBV developed into full-blown mononucleosis — people like Todd, whose case of mono in high school was so severe that he was briefly hospitalized. Could the End of MS Be on the Horizon? BY CARI WADE GERVIN A S A NE W LONGITUDINAL STUDY SHOWS A DEFINITIVE CONNECTION BE T WEEN THE EPSTEIN-BARR VIRUS AND MULTIPLE SCLEROSIS, RESE ARCH TURNS TO VACCINES, NE W TRE ATMENTS — AND THE FURTHER ROOTS OF WHAT CAUSES THE DISE A SE. 1 4

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