MDNews - Cleveland-Akron-Canton

January/February 2014

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RECENT RESEARCH NEW DRUG TARGET COULD PREVENT DIABETES, OBESITY drug target for the battle against obesity and related disorders. The search for a 'magic pill' children, ages 6 to 19, over eight years. Recently, a protein called ABHD6 was to prevent excessive weight gain has long been Researchers used BMI, or body mass index, to discovered to promote obesity and diabetes. sought after. These new findings suggest that measure weight trends. The protein is thought to regulate the brain's drugs inhibiting ABHD6 may simultaneously endocannabinoid system, which is involved in activate fat burning, increase physical activity, their weight problems through puberty. In ad- a variety of processes, including metabolism, and block the formation of new fat in the liver." dition, the study showed Children with weight The study looked at the records of 760 The study found children do not outgrow craving and hunger. problems before puberty are 20 times more New research from Cleveland Clinic's likely to have weight problems after puberty. Children who are in the "normal" weight cat- the function of this protein in animal models NEW STUDY SHOWS CHILDREN DO NOT OUTGROW OBESITY protects against all diseases driven by eating New research out of The MetroHealth System 4 times more likely of having abnormal weight a high-fat diet, including obesity, diabetes and shows that most children do not outgrow an after puberty liver disease. These studies suggest a new overweight/obese status after puberty. The biological pathway for preventing obesity, ac- study, published recently in The Journal of Stager, MD; David C. Kaelber, MD, PhD, MPH, cording to Cleveland Clinic research published Obesity and Weight Loss Therapy, indicates a say the study stresses the need to improve today in Cell Reports. need for improved earlier identification of and how the medical community identifies over- intervention for pre-puberty overweight and weight/obese children in order to intervene obese children. before they hit puberty. ■ Lerner Research Institute shows that blocking J. Mark Brown, PhD, who led the study, says, "We have identified ABHD6 as a new potential egory but on the high end before puberty are Authors Matthew Clark, MD; Margaret Collective Experience. Collaborative Culture. Creative Solutions. Innovative Solutions for Your Health Care Business With a keen understanding of the operations, market trends and economics of the health care industry, Brouse is poised to proactively counsel and advise a wide array of health care clients, including: n■ Multi- and single-physician groups n■ Home Health Care Providers n■ Hospitals & Health Systems n■ Medical Device Companies n■ Ancillary Service Providers n■ Mental Health Service Providers n■ Long Term Care Facilities n■ Durable Medical Equipment & Supply Companies For more information, please contact: Daniel K. Glessner, Esq., Practice Chair Christopher M. Huryn, Esq., Partner or 330.535.5711 x316 dglessner@brouse.com 330.535.5711 x389 churyn@brouse.com Akron n Cleveland n Lorain County n www.brouse.com

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