Issue link: https://viewer.e-digitaledition.com/i/670777
FE ATURES STUBBORN DEATH RATE SPURS CALLS FOR FRESH FOCUS ON PANCREATIC CANCER 06 W hile pancreatic cancer is not among the most common cancers, it is one of the deadliest. Yet it receives comparatively little research funding — something advocates and scientists say has to change. DRUG ALTERS APPROACH TO TREATING ADVANCED MELANOMA 16 Restoring the body 's ability to detect and attack cancer is the focus of a newer class of drugs that is transforming how physicians fight advanced melanoma. Pembrolizumab is leading the charge. SPECIAL CLINICAL SECTION: WOMEN'S HE ALTH RESEARCH HIGHLIGHTS BENEFIT OF OVARIAN TISSUE TRANSPLANTATION AFTER CANCERTREATMENT 10 Clinicians have long suspected that cryopreservation of ovarian tissue prior to cancer treatment for transplantation of the tissue afterward is an e•ective and safe means of maintaining fertility. A Danish study confirms that. THE PERIL OF QUITTING: ASSESSING THE RISK OF ENDING HORMONE REPLACEMENTTHERAPY 12 Potentia l dangers of hormone replacement therapy have gained a great dea l of attention in recent years, but ha lting the therapy may entail significant medica l risk as well. DATA VAULT 13 A roundup of statistics about women's hea lth SPECIAL CLINICAL SECTION: NEUROLOGY A WAY FORWARD IN TREATING PRIMARY-PROGRESSIVE MULTIPLE SCLEROSIS? 20 Roughly 15 percent of people with multiple sclerosis have the primary-progressive form of the disease, and e•ective treatments for these patients have been scarce. Results from a phase 3 study of the drug ocrelizumab may change that. NEW TECHNIQUE USES BLOOD FLOW TO FIGHTSTROKE 22 A novel use of a stent and nanoparticles coated with tissue plasminogen activator holds promise for rapidly dissolving blood clots while minimizing vascular injury. THAT'S NEWS 23 A roundup of news related to neurolog y DEPARTMENTS PRACTICE MANAGEMENT 05 BUSINESS OF MEDICINE 08 FINANCE 14 PRODUCT SPOTLIGHT 18 THE LINK 24 10 contents ///// MAY/JUNE 2016 20 16 ON THE COVER