MDNews - Mid Penn

COVER FE ATURE RADIOFREQUENCY ABLATION FOR THYROID NODULES 08 For benign nodules, radiofrequency ablation provides a minima lly invasive a lternative to surgery. NATIONAL FE ATURE EXPLORING THE VALUE OF PATIENT NAVIGATION 05 The service has benefits for hea lthcare systems and patients a like. FE ATURES FLUORESCENT VISUALIZATION IMPROVES GLIOMA TUMOR REMOVAL 06 New imaging approach a llows more effective tumor resection. A SOPHISTICATED SOLUTION TO ADDRESS GALLSTONES 07 Penn State Hea lth offer patients who are not candidates for ga llbladder remova l the opportunity to live life drain-free. please do not delete the folios! please check that design elements work with the folio and street signs, and leave them on the page until the mechanical process is complete special section tabs are only used for Dan's books - please turn them off before creating PDFs L-DOPA Challenge Test May Predict Motor Function Response study published in Frontiers in Human Neuroscience suggests L-DOPA challenge test prior to DBS surgery may predict function response after surgery, depending on whether the in the subthalamic nucleus (STN) or globus pallidus (GPi). Although the study was small, the analysis showed a correlation patients who responded to the test prior to GPi-DBS improved motor function. There was no correlation between response and motor function for patients with STN-DBS However, a better response indicated better non-tremor unlike GPi-DBS implants. PROMISING CLINICAL IMPLICATIONS Ince and his colleagues recorded the response of the brainwaves at the same time as they were stimulating the brain, which a llowed them for the first time to eliminate the amplitude artifacts that mask the full neural response. While the results need to be validated with a larger study, the implications of the new process could change the way Parkinson's is treated, and possibly other neurological conditions. "There's quite an interest from the industry into this scholar- ship because it has huge clinical implications," Ince says. If further studies with subthalamic nucleus DBS continue to be promising, additional research will follow to determine if similar patterns exist with globus pallidus interna DBS. "Other indications such as essential tremor or psychiatric indications and related targets need to be investigated," Ince says. "This will open a new route in terms of research for the optimization of DBS technology advances, as electrodes are becoming more and more complex." n 08 contents /////// INNOVATION 2021 SPECIAL CLINICAL SECTION: DEGENER ATIVE DISE ASE DENOSUMAB FOR BONE DENSITY LOSS: BENEFITS VS. RISKS 10 The medication has had problems with bone density loss and fracture after patients discontinue therapy, but it may provide a va luable solution for a variety of indications. DEEP BRAIN STIMULATION AT SOME FREQUENCIES MAY BE AS EFFECTIVE AS MEDICATION FOR PARKINSON'S DISEASE 12 Researchers are refining their understanding of which frequencies best treat Parkinson's disease. SPECIAL CLINICAL SECTION: R ADIOLOGY MICROBUBBLES MAY BOOST RESPONSE TO TRANSARTERIAL RADIOEMBOLIZATION FOR THE MOST COMMON FORM OF LIVER CANCER 14 Popping microbubbles — a process known as inertial cavitation — in the vicinity of microbeads delivering transarteria l radioembolization ma kes tumors more sensitive to treatment, studies suggest. 12 07 ON THE COVER

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